- Title
- Antibacterial Properties of Zinc Oxide Nanoparticles Synthesized by the Supernatant of Weissella Confusa UPM22MT04
- Creator
- AL-Tameemi, A. I.; Masarudin, M. J.; Rahim, R. A.; Timms, V.; Neilan, B.; Isa, N. M.
- Relation
- Iraqi Journal of Agricultural Sciences Vol. 54, Issue 5, p. 1209-1222
- Publisher Link
- http://dx.doi.org/10.36103/ijas.v54i5.1816
- Publisher
- Jami'at Baghdad,University of Baghdad
- Resource Type
- journal article
- Date
- 2023
- Description
- This study was aimed to produce zinc oxide nanoparticles (ZnO-NPs) using the supernatant of Weissella confusa UPM22MT04 and assess their effectiveness in inhibiting methicillin-resistant Staphylococcus aureus (MRSA). An isolate of Weissella confusa UPM22MT04 was isolated from a wastewater treatment plant in Johor, Malaysia, and was utilized to synthesize ZnO-NPs. The synthesized ZnO-NPs were characterized through several techniques, including UV-visible spectroscopy, Fourier-transform infrared spectroscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, and dynamic light scattering. Monodisperse spherical ZnO-NPs of 1.7 - 7.9 nm were obtained with 0.1 M zinc nitrate at 80°C. The biosynthesized ZnO-NPs exhibited vigorous inhibitory activity against MRSA. Results found that ZnO-NPs inhibited MRSA at a minimum concentration of 0.625 mg/mL and were bactericidal at a minimum concentration of 1.25 mg/mL. In MTT assays, ZnO-NPs showed no toxicity to HS-27 fibroblasts. The supernatant of Weissella confusa UPM22MT04 could be used to synthesize ZnO-NPs, which are an antibacterial agent, eco-friendly and non-toxic.
- Subject
- biosynthesis; Weissella confusa; ZnO-NPs; antibacterial activity; methicillin-resistant Staphylococcus aureus (MRSA); SDG 3; SDG 6; SDG 17; Sustainable Development Goals
- Identifier
- http://hdl.handle.net/1959.13/1493569
- Identifier
- uon:53588
- Identifier
- ISSN:0075-0530
- Language
- eng
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